Each Vial contains 1,500 international units of Hyaluronidase. A white, sterile freeze-dried powder for solution for injection or infusion.
Mesolike Hyaluronidase 1500 I.U. can be used to enhance permeation of subcutaneous or intramuscular injections, local anaesthetics and subcutaneous infusions and to promote resorption of excess fluids and blood in the tissues also Mesolike Hyaluronidase 1500 I.U. is particularly suitable for treating cellulite because it is an active ingredient that attacks the fibrosis associated to this problem. Its mechanism of action is to prevent the hyperpolymerization of glycosaminoglycans responsible for water retention. Hyaluronidase depolymerises sulfuric chondroitin and hyaluronic acid from the ground substance of connective tissue. Also enhances cellular exchange in triglycerides accumulated within adipocytes. The result of its action is the removal of retained fluids and the reduction of the adipocytes volume, being that triglycerides accumulated there become free fatty acids and glycerol, elements that cover the energy requirements of the organism. Furthermore, hyaluronidase facilitates removal of intraderm water bags and promotes the penetration of other active substances through the skin.
Extravasation: Where dispersal rather than localisation is indicated, 1500iu of Hyaluronidase in 1ml up-to 1.5ml water for injections or normal saline infiltrated into the affected area as soon as possible after the extravasation is not.